Translational Bioinformatics Scientist Job at Astellas Pharma, Inc., Cambridge, MA

K3QzWm5UcTh5QkRSb0NQd3ZPSHJlbFhzZ2c9PQ==
  • Astellas Pharma, Inc.
  • Cambridge, MA

Job Description

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians. If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at .

This position is based in Cambridge, MA. Remote work from certain states may be permitted in accordance with Astellas' Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.

Purpose and Scope:

Responsible for providing computational biology and bioinformatics expertise to translational research, patient selection strategy and clinical biomarker analyses for multiple drug discovery and development programs. Develop computational tools, perform hands-on data analyses and generate analysis reports. Responsibilities also include developing new bioinformatics and computational capabilities to support new modalities and therapeutic focus areas.

Essential Job Responsibilities:
  • Collaborate with Global Translational Medicine Leads to design and execute analysis plans that address key translational research questions from asset teams. These may include indication and/or patient selection, biomarker discovery (pharmacodynamic, prognostic, and predictive, and disease biomarkers)
  • Identify and leverage relevant public and proprietary datasets to support translational objectives, and effectively communicate findings and insights to cross-functional asset teams.
  • In alignment with current and future portfolio needs, partner with Global Translational Bioinformatics Leads to develop and implement novel analytical methodologies and platforms, such as spatial transcriptomics workflows and integrated data portals, to enable cutting-edge translational research.
  • Support the ingestion, curation, and archiving of large-scale omics and imaging datasets generated from Astellas-sponsored clinical trials and academic collaborations.

Qualifications:

Required
  • Ph.D. in computational biology, bioinformatics, or other biomedical sciences with 4-6 years' experience in applying bioinformatics or computational approaches to drug discovery/development, preferably in a biopharma setting
  • Strong hands-on experience with Python, R, or similar languages commonly used in bioinformatics or image analysis
  • Demonstrated expertise in analyzing multi-omics and clinical data to support research into disease mechanisms, patient stratification and biomarker discovery
  • Experience in at least one of the following domains: advanced spatial transcriptomics analytics (oncology), advanced imaging analytics (oncology), or ophthalmology clinical imaging biomarker analytics
  • Strong problem-solving mindset and willingness to work collaboratively in cross-functional clinical research environments
  • Good communication skills, especially in explaining technical concepts to non-technical stakeholders.
  • Eager to learn new technologies and passion in translational / clinical research

Preferred
  • Exposure to deep learning frameworks (e.g., PyTorch, TensorFlow) and experience training or fine-tuning models on oncology imaging (H&E, IHC, mIF, etc) or omics data is a plus
  • Some experience in ophthalmic imaging analysis (OCT, FAF, etc.) is a plus but not required

Salary Range

$130K - $170K (NOTE: Final salary could be more or less, based on experience)

Benefits:
  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation, Sick time, plus national holidays including Heritage Days, and Summer and Winter Breaks
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Referral bonus program

Job Tags

Full time, Summer holiday, Remote work,

Similar Jobs

BlackRock

VP, Product Manager - Portfolio Management Job at BlackRock

**About this role****Team Overview**BlackRock SMA Solutions helps clients customize portfolios for unique tax, values-alignment, or investment exposures across direct indexing, fixed income, active equity, and multi-asset. We deliver world-class service to all of our... 

Milton Hershey School

Elementary Band Teacher Job at Milton Hershey School

Description: Milton Hershey School (MHS) is one of the world's best private schools, where students in pre-K through 12th grade from disadvantaged backgrounds...  ...to schedule and complete an additional duty to their teaching schedules. Qualifications: Bachelors degree in... 

Trueline

Plumbing/HVAC Estimator Job at Trueline

 ...Trueline is seeking an HVAC/Plumbing Estimator to join their team in New Britain, CT.This estimator will focus on complex systems...  ...years of mechanical estimating experience ~ Prior work with unionized field teams ~ Experience estimating large institutional projects... 

Get It - Marketing

VP of Demand Generation, Marketing - Remote | WFH Job at Get It - Marketing

Vice President of Marketing (Remote) About the Company We are a fast-growing SaaS company specializing in SMS solutions designed for marketing...  ...campaigns to ensure best-in-class execution. Partner with digital marketing agencies to refine website performance, landing... 

American Food Service Depot

Warehouse Picker Job at American Food Service Depot

Position Overview: Now Hiring : Warehouse Picker Location: Philadelphia, PA Compensation: $15 - $16 Hourly Warehouse Picker Job Purpose: Manages invoiced orders from the shipping clerk. Physically pulls inventory from the shelves and delivers it to the...